Department Faculty and Their Research

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Jonathan Beckwith, Ph.D., Professor

Bacterial genetics: protein folding, protein secretion, protein disulfide bond formation and reduction, cytoplasmic redox pathways.

Thomas G. Bernhardt, Ph.D., Assistant Professor

Bacterial genetics; mechanism of cell division and its spatial and temporal regulation; cell wall construction

John Collier, Ph.D., Professor

Protein structure and function; bacterial exotoxins; protein-membrane interactions.

Ronald Desrosiers, Ph.D., Professor

Animal virology; simian herpesvirus and retroviruses; molecular biology of viral-induced diseases of monkeys.

David T. Evans, Ph.D., Assistant Professor

Virology and Immunology; primate lentiviruses; mechanisms of protective immunity and viral pathogenesis.

Michael Farzan, Ph.D., Associate Professor

Receptors and entry processes of retroviruses, flaviviruses, and coronaviruses, and developing mass spectrometry as a technique for observing the adaptive immune responses to HIV-1 and SIV.

Dan Fraenkel, Ph.D., Professor Emeritus

Microbial metabolism, yeast glycolysis.

Lee Gehrke, Ph.D., Professor

Regulation of gene expression through RNA-protein interactions and translation-level control mechanisms.

Darren Higgins, Ph.D., Professor

Host-pathogen interactions: intracellular bacterial pathogens; mechanisms of virulence and the host immune response.

Ann Hochschild, Ph.D., Professor

Bacterial transcription and its regulation; genetic approaches for studying protein-protein interactions.

Deborah Hung, M.D., Ph.D., Assistant Professor

Chemical biology, bacterial genetics and genomics; regulation of virulence, latency and drug tolerance.

Welkin Johnson, Ph.D., Assistant Professor

Replication and pathogenesis of retroviruses.

Dennis Kasper, M.D., Professor

Biology of bacterial polysaccharides including immunology, virulence, structure, and use as vaccines and immunomodulators.

Elliott Kieff, M.D., Ph.D., Professor

Virology: molecular biology of Epstein-Barr virus infection and growth transformation of B lymphocytes.

David Knipe, Ph.D., Professor, Vice Chair of Faculty Development and Education

Virology: molecular biology of herpes simplex virus productive and latent infection; innate immune responses to viruses; viral vaccines.

Roberto Kolter, Ph.D., Professor

Microbial molecular genetics: bacterial biofilms, interspecies interactions, genome evolution.

Stephen Lory, Ph.D., Professor

Bacterial pathogenesis: global gene regulation during host-pathogen interactions, genomics, mechanisms of secretion of bacterial virulence factors.

John Mekalanos, Ph.D., Professor, Department Chair

Protein chemistry and bacterial genetics; biochemistry of bacterial toxins; genetic analysis of bacterial virulence.

Max Nibert, M.D., Ph.D., Professor

Virology: reoviruses and rotaviruses; structure and assembly, entry, transcription and RNA processing, interactions with cells, pathogenesis.

David Rudner, Ph.D., Assistant Professor

Spore formation in B. subtilis. Cell-cell signaling, determinants of subcellular protein localization, chromosomal organization and segregation.

Michael Starnbach, Ph.D., Professor

T-lymphocyte responses to bacterial pathogens; subcellular compartmentalization of bacterial antigens.

Charles Stiles, Ph.D., Professor

Cell biology: regulation of gene expression by animal cell growth factors.

Suzanne Walker, Ph.D., Professor

Chemical biology applied to microbial systems; antibiotic mechanisms; enzyme structure, function, inhibition, and engineering.

Sean Whelan, Ph.D., Associate Professor

Molecular biology of the non-segmented negative-sense (NNS) RNA viruses.

Priscilla L. Yang, Ph.D., Assistant Professor

Chemistry and biology of host-virus interactions.

 

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